منابع مشابه
Monoclonal antibodies against bovine growth hormone.
A number of mouse x mouse hybridomas producing monoclonal antibodies (MAbs) against bovine growth hormone (bGH) were prepared by fusion of spleen cells from bGH-primed mice (Balb/c) with non-secretory mouse myeloma cells (PAIOP3) and characterized. MAbs obtained from three fusion experiments belonged to IgM, IgG1 and IgG2b class/subclass of antibodies. Cross-reaction studies indicated that gene...
متن کاملStructural Studies on Bovine Growth Hormone
Purified bovine growth hormone, consisting of a single polypeptide chain, has been found to contain NHz-terminal alanine, phenylalanine, and methionine in nearly equal amounts. The minimum molecular weight calculated from its amino acid composition is 20,846. Five unique fragments have been prepared from bovine growth hormone by cleavage at 4 methionyl residues with cyanogen bromide. In the ord...
متن کاملAnother look at bovine growth hormone.
-In a clinical investigation of postoperative survival after primary surgery for stomach cancer, 390 patients were registered since 1974. The potential prognostic parameters examined within the first days of hospitalization for primary resection included age of the patients, operability, tumour extension (TNM classification) and tumour stages I-IV (UICC). Statistical treatment of the data revea...
متن کاملSeparation and properties of multiple components of bovine growth hormone.
Starch gel electrophoresis at alkaline pH of bovine growth hormone preparations from a number of sources has revealed a common pattern characterized by a major anionic component and two minor faster moving components. Gel tiltration studies of the hormone indicate that all three components are of similar molecular weight. A method has been developed for separation of the components by chromatog...
متن کاملConformational similarity of ovine prolactin and bovine growth hormone.
The behavior and properties of ovine prolactin have been evaluated by measurements of fluorescence, polarization of fluorescence, absorption, optical rotation, and circular dichroism. The helical content of the native molecule at pH 8 is 60 per cent as determined by circular dichroism. Three molecular transitions have been followed. The one in acid affects only 20 per cent of the helical residu...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1973
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1973.tb02971.x